李扬，博士，硕士生导师，校聘副教授
地址：武汉市东湖新技术开发区光谷一路206号，武汉工程大学化工与制药学院
邮编：430205
邮箱: lyyy9281015@163.com，lyyy@wit.edu.cn
教育背景
2017/09-2022.06，武汉大学，药学，博士 （导师：洪学传教授）
2013/09-2017/06，武汉工程大学，制药工程，学士
工作履历
2024/08-至今，武汉工程大学，校聘副教授
2022/07-2024/07，华东理工大学，博士后 （合作导师：马骧教授）
科研项目
1. 国家自然科学基金青年基金，22307036，30万，主持
2. 中国博士后科学基金面上项目，2023M731079，8万，主持，已结题
3. 上海市超级博士后资助项目，2022161，30万，主持，已结题
4. 武汉工程大人才引进项目，50万，主持
研究领域
药物化学：诊疗探针与药物递送
化学生物学：光学探针（如荧光和磷光探针等）与生物成像/传感
精细化工：有机功能染料（如近红外荧光与有机室温磷光材料等）
近五年发表SCI论文20余篇，其中以第一/通讯作者（含共同）在Chem. Rev., Angew. Chem. Int. Ed.，Chem，Nat. Sci. Rev.，J. Control. Release，J. Med. Chem.，CCS Chem., Chem. Sci.等期刊发表10余篇，他引超1200次。担任精细化工杂志青年编委，Dyes and Pigments、中国医药工业杂志等国内外学术期刊审稿人。
代表性一作/通讯论文：
[1] Yang Li, Xiang Ma* et al. Activatable red/near-infrared aqueous organic phosphorescence probes for improved time-resolved bioimaging. National Science Review, 2025, 12, nwae383. (ESI高被引, 一区top， IF= 17.1)
[2] Qihang Ding, Yang Li*, Jian Tian*, Jong Seung Kim* et al. MitoSiege-driven catalase collapse: A GSH-responsive, mitochondria-targeted COF prodrug for amplified chemodynamic therapy. Angewandte Chemie International Edition. 2025 e202509183. Doi: 10.1002/anie.202509183. (一区top， IF= 16.9)
[3] Yang Li, Xiang Ma* et al. Aqueous up-conversion organic phosphorescence and tunable dual emission in a single-molecular emitter. Chemical Science, 2025, 16, 6290-6297. (一区top, IF= 7.4)
[4] Qihang Ding, Yang Li*, Min Hee Lee*, Jong Seung Kim*. Regulated cell death mechanisms in mitochondria-targeted phototherapy. Journal of Controlled Release, 2025, 382, 113720. (一区top, IF= 11.5)
[5] Yang Li, Xuechuan Hong, Yuling Xiao* et al. Organic NIR-II dyes with ultralong circulation persistence for image-guided delivery and therapy. Journal of Controlled Release, 2022, 342, 157-169. (一区top, IF= 11.5)
[6] Yang Li, Xuechuan Hong*, Yuling Xiao* et al. Self-assembled NIR-II fluorophores with ultralong blood circulation for cancer imaging and image-guided surgery. Journal of Medicinal Chemistry, 2022, 65, 2078–2090. (一区top, IF= 6.8)
[7] Yang Li, Xuechuan Hong* et al. Small-molecule fluorophores for NIR-IIb imaging and image guided therapy of vascular diseases. CCS Chemistry, 2022, 4, 3735–3750. (一区top, IF= 9.2)
[8] Ao-Pei Peng, Yang Li*, Shuang-Xi Gu*, Yuan-Yuan Zhu* et al. Efficient synergistic recognition of D/L-cysteine and zinc ions using a chiral chemosensor. Sensors and Actuators B: Chemical, 2025, 442, 138062. (一区top, IF= 8.0)
[9] Yi-Xin Zhang, Yang Li*, Shuang-Xi Gu*, Yuan-Yuan Zhu* et al. Enantioselective recognition of amino acids in water using emission-tunable chiral fluorescent probes. Chinese Chemical Letters, 2025, Doi: 10.1016/j.cclet.2025.111500. (一区top, IF= 8.9)
[10] Yang Li, Xuechuan Hong and Yuling Xiao* et al. Novel NIR-II organic fluorophores for bioimaging beyond 1550 nm. Chemical Science, 2020, 11, 2621-2626. (ESI高被引, 一区top, IF= 7.4)
[11] Yang Li, Xuechuan Hong* et al. A bright NIR-II fluorescence probe for vascular and tumor imaging. Journal of Visualized Experiments, 2023, e64875.
[12] Yishen Liu, Yang Li, Xuechuan Hong* et al. Versatile Types of Inorganic/Organic NIR-IIa/IIb Fluorophores: From Strategic Design toward Molecular Imaging and Theranostics. Chemical Reviews, 2022, 122, 209–268. (ESI高被引，共同一作，一区top, IF= 55.8)
[13] Qihang Ding, Xiaoyu Xu, Yang Li, Jong Seung Kim* et al. Diverse interactions between AIEgens and biomolecules/organisms: Advancing from strategic design to precision theranostics. Chem, 2024, 10, 2031-2073. (共同一作，一区top, IF= 19.6)
[14] Xue Qiao, Yang Li, Xuechuan Hong* et al. A near-infrared IIb fluorophore for in vivo imaging and image-guided therapy of ischemic stroke. Dyes and Pigments, 2023, 212, 111123. (共同一作)
授权专利
申请中国专利7件，已获批4件
1. ZL202110115536.8，可调控代谢的有机荧光小分子化合物及其制备方法和应用
2. ZL202110115537.2，可在体内长时间循环的有机荧光小分子化合物及其制备
3. ZL202110748816.2，具有聚集诱导发光性质的近红外二区荧光化合物及其制备方法和应用
4. ZL202110749756.6，1500 nm以上发射荧光的有机荧光小分子化合物的制备和应用
