王海峰，博士，副教授，硕士生导师
地址：湖北省武汉市东湖新技术开发区光谷一路206号
邮编：430205
E-mail: skytacle@139.com
教育背景
2013.9-2017.7，复旦大学，化学系，博士
2005.9-2008.7，西北师范大学，化学化工学院，硕士
工作履历
2019.12-至今，武汉工程大学，化工与制药学院，讲师/副教授
2017.7-2019.11, 周口师范学院，化学化工学院，讲师
2008.7-2013.7，制药企业，从事新药开发和药物合成工艺研发
研究领域
1.天然产物和手性药物合成研究: 天然甾体类化合物和抗病毒药物的不对称合成
2.基于微通道连续流动化学的药物合成工艺研究：高端磷系化学品的绿色制造
3.卡宾化学新反应研究：基于卡宾前体的功能性有机分子合成研究
科研项目
1.湖北省自然科学基金一般面上项目, 主持，
2.湖北省教育厅科学研究计划指导性项目，主持
3.河南省科技厅科技攻关项目，主持
4.东华理工大学江西省合成化学重点实验室开放基金项目，主持
学术成果
部分研究论文：
(1) Huan Li, Zhimin Xia, Lewan Li, Jie Zeng, Jian Lv, Haifeng Wang*, Shuangxi Gu*, and Fener Chen*. Regioselective Cleavage and Reconffguration of C−S Bonds with Diazo Compounds. Org. Lett. 2024, 26, 8405-8409.
(2) Lewan Li, Mengxiang Luo, Shuntian Liu, Jian Lv, Jie Zeng, Qiongjiao Yan, Jie Liao, Haifeng Wang*, Shuangxi Gu*. Rapid and General Access to α‐Halogenated Carbonyl Compounds Using Amidine Halide Salts as Halogen Sources under Mild Conditions. Eur. J. Org. Chem. 2024, DOI: 10.1002/ejoc.202401111.
(3) Shuqi Zhou, Chunyan Li, Jie Zeng, Jian Lv, Jie Liao, Haifeng Wang*, Qiongjiao Yan* and Shuangxi Gu*. Al(OTf)3‑Catalyzed Regioselective N2−Arylation of Tetrazoles with Diazo Compounds. J. Org. Chem. 2024, 89, 7859-7864.
(4) Mengxiang Luo, Lewan Li, Shixin Chen, Qiongjiao Yan, Jian Lv, Jie Zeng, Haifeng Wang*, Shuangxi Gu* and Fener Chen*. Synthesis of 2,4-Disubstituted Oxazoles and Thiazoles via Brønsted Acid-Catalyzed Cyclization of α‑diazoketones with Amides. J. Org. Chem. 2024, 89, 7, 5038-5048.
(5) Chunyan Li, Tonghui Zhang, Menghua Dong, Lewan Li, Huan Li, Jie Zeng, Jian Lv, Haifeng Wang*, Shuangxi Gu.* Brønsted acid-catalyzed selective alkylation of tetrazoles with acetone. Tetrahedron Lett. 2024, 151, 155327.
(6) Zhimin Xia, Chunyan Li, Mengxiang Luo, Shuangxi Gua, Qiongjiao Yan, jian Lv, jie Zeng, Haifeng Wang*. Substrate-Controlled Regioselective Alkylation of 4-Hydroxycoumarin with Diazo Compounds through TfOH Catalysis. Synlett, 2024, 35,1584-1590.
(7) Jingru Jin, Chunyan Li, Rui Wang, Zhimin Xia, Qiongjiao Yan, Wei Wang, ShuangXi Gu, Haifeng Wang*, and Fener Chen*. Chemodivergent Synthesis of Sulfonamide and Sulfones from N-Tosylhydrazones by Switching Catalyst and Temperature. Org. Lett. 2023, 25, 32, 6012-6017.
(8) Chunyan Li, Rui Wang, Li Huang, Jiale Chen, Jingru Jin, Qiongjiao Yan, Wei Wang, Haifeng Wang*, and Fener Chen*. TfOH-Catalyzed Regioselective S–H Insertion of Cyclic Thioamide Derivatives with Diazo Compounds at Room Temperature. J. Org. Chem. 2023, 88, 7, 4452-4457.
(9) Zhewei Yan, Hangli He, Dabiao Yuan, Qiongjiao Yan, Wei Wang, Haipeng Jiang, Haifeng Wang*, Fener Chen*. Regioselective O-Alkylation of 2-Pyridones by TfOH-catalyzed carbenoid insertion. Chem. Commun. 2023, 59, 106-109.
(10) Mengxiang Luo, Rui Wang, Yang Li, Jiahao Gong, Shuangxi Gu, Qiongjiao Yan, Jian Lv, Jie Zeng, Wei Wang, Haifeng Wang*, Fener Chen*. TfOH-Catalyzed Regioselective Alkylation of Hydroxybenzotriazole with Diazo Compounds and Further Base Facilitated Elimination under Batch and Flow Conditions. Asian J. Org. Chem. 2023, e202300511.
(11) Rui Wang, Hangli He, Qiongjiao Yan, Wei Wang, Haifeng Wang*, Fener Chen*. TfOH-Catalyzed Three-Component Synthesis of Dithiocarbamates from α-Diazoesters under Continuous Flow Conditions. J. Flow Chem. 2023, 13, 1-8.
(12) Hangli He, Jingyu Yan, Jingru Jin, Zhewei Yan, Qiongjiao Yan, Wei Wang, Haipeng Jiang, Haifeng Wang* and Fener Chen*. TfOH-catalyzed regioselective N2-Alkylation of indazoles with diazo compounds. Chem. Commun. 2022, 58, 6429-6432.
(13) Hangli He, Zhewei Yan, Qiongjiao Yan, Wei Wang, Haifeng Wang*, Fener Chen*. Solvent Controlled Three-Component Reaction of Diazo Compounds for the Synthesis of Hydrazone Compounds under Brønsted Acid Catalysis, New J. Chem. 2022, 46, 22513-22517.
(14) 葛 锐, 朱园园, 王海峰*, 古双喜*. 手性化合物绝对构型确定的方法与应用, Chin. J. Org. Chem. 2022, 42, 424-433.
(15) Haifeng Wang*, Xiangli Sun, Manman Hu, Xiaoyi Zhang, Lele Xie, Shuangxi Gu*. Bromination of α-diazo Phenylacetate Derivatives Using Cobalt (II) Bromid, Adv. Synth. & Catal. 2020, 362, 3347-3351.
(16)Haifeng Wang, Shuangxi Gu, Qiongjiao Yan, Li Ding, Fen-Er Chen*. Asymmetric Catalysis in Synthetic Strategies for Chiral Benzothiazepines. Green Synthesis and Catalysis, 2020, 12-25.
