刘慧，博士，教授，博士生导师
地址： 湖北省武汉市东湖新技术开发区光谷一路206号
邮编：430205
E-mail: 2806358119@qq.com
教育背景
2001.09－2007.01 中国科学院上海有机化学研究所 博士
1997.09－2001.06 武汉大学化学与分子科学学院 学士
工作履历
2025.12－至今 武汉工程大学化工与制药学院 教授
2017.12－2025.11 武汉工程大学化工与制药学院 副教授
2013.12－2017.11 武汉工程大学化工与制药学院 讲师
2010.10－2013.09 武汉信嘉和诚药物化学有限公司 研发总监
2009.03－2010.09 中美华世通生物医药有限公司 高级科学家
2007.07－2008.08 法国原子能研究所（CEA-Grenoble） 博士后
研究领域
1) 药物分子设计及其制剂配方筛选；
2) 制药工艺优化及其质量控制；
科研项目
2014.01-2016.12 国家自然科学青年基金 25万 主持 已结项
2022.06-2025.05 湖北省重点研发项目 100万 主持 已结项
学术成果
近期代表性论文：
1. Hong-Lin Zhong; Hao Li; Li-Xiang Tan; Hui Liu*; Acyclic cucurbit[n]uril-based sensor array for identification and discrimination of antimicrobial agents, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2026, 348: 127116-127123.
2. Hui Liu*; Shixiang Zeng; Yujin Li; Zhiping Liu; Synthesis of nitroso derivatives of dihydropyridine calcium channel blockers, Organic Process Research & Development, 2025, 29: 1837-1842.
3. Yisu Liu; Guangpu Wu; Jiang Zhu; Yao Jiang; Hui Liu*; Synergistic effect of the hybrid compounds of cationic pillararene and an efflux pump inhibitor against gram-negative bacteria, RSC Medicinal Chemistry, 2025, 16: 3778-3786.
4. Yanqing Jin; Yisu Liu; Jiang Zhu; Hui Liu*; Pillararenes: a new frontier in antimicrobial therapy, Organic Biomolecular Chemistry, 2024, 22: 4202-4211.
5. Hong-Lin Zhong; You-Jia Guo; Hang Yuan; Hui Liu*; Acyclic phosphonate hosts for the detection of antimicrobial medicines, New Journal of Chemistry, 2024, 48: 18040-18044.
6. Zhen Fu; Yanqing Jin; Bingqian Xie; Hui Liu*; Effect on the conformation of monosubstituted pillar[5]arene: solvent, temperature, concentration and linker length, Organic Biomolecular Chemistry, 2023, 21: 7546-7552.
7. Hui Liu*; You-Jia Guo; Acyclic cucurbiturils and their applications, Journal of Inclusion Phenomena and Macrocyclic Chemistry, 2022, 102: 723-733.
8. Hui Liu*; Zu-Zheng He; Lei Yu; Jun Ma; Xue-Pin Jin; Improved solubility and stability of rifampicin as an inclusion complex of acyclic cucurbit[n]uril, Journal of Inclusion Phenomena and Macrocyclic Chemistry, 2021, 101: 111-120.
9. Hui Liu*; Complexation of bipyridinium guests in the cavity of acyclic cucurbit[n]uril receptor, Supramolecular Chemistry, 2019, 31(4): 451-456.
10. Ganlin Hu; Chunxin Yang; Hui Liu*; Jianming Shen; Pillar[5]arene- functionalized paper as a fluorescent sensor for cyanide ions in water, New Journal of Chemistry, 2019, 2019(43): 11474-11476.
11. Hui Liu*; Fei Lv; Yuan Liu; Improved Preparation of Silodosin, Organic Preparations and Procedures International, 2019, 2019(51): 287-293.
12. Hui Liu*; Ji-Qiang Tu; Cheng-Hua Zhang; Qiao-Ting Xiao; Tian-Hua Wang; Xiu-Lian Ju; Selective complexation of di-n-hexylammonium salts by tailed porphyrin host. New Journal of Chemistry, 2016, 40: 5679-5682.
13. Hui Liu*; Wen-Yue Zheng; Xian-Fei Ou; Xiu-Lian Ju; An efficient synthesis of dimemorfan from dextromethorphan. Organic Preparations and Procedures International, 2015, 47: 214-219.
14. Hui Liu*; Zhan-Ting Li; Metalloporphyrin receptors for histidine-containing peptides. Chinese Chemical Letters, 2014, 25: 659-662.
授权专利:
1. 刘慧；安佰谦；付臻；祝宏；一种恩康唑晶体及其制备方法和应用，ZL202211682523.X
2. 刘慧；郭又嘉；开环葫芦脲磷酸盐化合物及其制备和在药物增溶中的应用，ZL202210249153.4
3. 刘慧；何祖政; 一种高水溶性利福平包合物及其制备方法, ZL202010711779.3
4. 刘慧; 胡甘霖; 沈建明; 一种柱芳烃修饰的氰离子荧光检测试纸及其制备方法、检测方法, ZL201811496890.4
5. 刘慧; 刘志平；吕飞；郑文钺；一种西洛多辛草酸盐的晶型及其制备方法，ZL201410652069.2
